Andrew Johnson (a former tailor who became president in 1865 after Abraham Lincoln's fatal shooting) and his wife, Eliza McCardle Johnson, had five kids during their 50-year marriage. They tied the knot when she was just 16. Eliza Johnson, a shoemaker's daughter, tutored her uneducated young husband in math and reading.
For more about presidential wives and kids, read:
The Families of the Presidential Candidates
For more on famous marriages, read:
Top 10 Midlife Marriages of 2011
Longest Celebrity Marriages
Shortest Celebrity Marriages
Famous Weddings from the Past
Once Was Not Enough: These Celebrities Married Multiple Times